Channelopathies in Heart Disease

Channelopathies in Heart Disease

Remme, Carol Ann; Thomas, Dierk

Springer International Publishing AG

09/2018

439

Dura

Inglês

9783319778112

15 a 20 dias

1030


ebook

Descrição não disponível.
Introduction.- Part 1: (Dys)function of cardiac ion channels. Cardiac sodium channel (dys)function and inherited arrhythmia syndromes.- Potassium channels in the heart.- Voltage-gated calcium channels and their roles in cardiac electrophysiology.- HCN channels and cardiac pacemaking.- Dysregulation of ionic homeostasis: relevance for cardiac arrhythmias.- Part 2: Cardiac channelopathies: clinical and genetic findings. Long and short QT syndromes.- Brugada syndrome: current perspectives.- Sinus node disease and cardiac conduction disease.- Catecholaminergic polymorphic ventricular tachycardia.- Idiopathic ventricular fibrillation and early repolarization.- Atrial fibrillation.- Genetic testing for inheritable cardiac channelopathies.- Part 3: Research into cardiac channelopathies: new avenues. Novel imaging techniques in cardiac ion channel research.- Transgenic animal models of cardiac channelopathies - benefits and limitations.- Induced pluripotent stem cell-derived cardiomyocytes: towards personalized therapeutic strategies?.
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Ion channels;Channelopathies;Electrophysiology;Cardiac arrhythmias;Cardiac disease;Computational modeling;induced pluripotent stem cells;iPSC;Cardiomyocytes;Animal models;Heart