Control and Prediction of Solid-State of Pharmaceuticals

Control and Prediction of Solid-State of Pharmaceuticals

Experimental and Computational Approaches

Bhardwaj, Rajni Miglani

Springer International Publishing AG

03/2018

238

Mole

Inglês

9783319801698

15 a 20 dias

454

Descrição não disponível.
Introduction.- Aims and Objectives.- Materials and Methods.- Development and Validation of High_Throughput Crystallization and Analysis (HTCAA) Methodology for Physical Form Screening.- Predicting Crystallizability of Organic Molecules using Statistical Modelling Techniques.- Exploring Crystal Structure Landscape of Olanzapine.- Exploring the Physical Form Landscape of Clozapine, Amoxapine and Loxapine.- Conclusions and Further Work.
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Physical Form Screening;Experimental Crystal Structure Landscape;Solid-State Diversity;Crystal Structure Predcition;Crystallizability, High-throughput Crystallisation;Olanzapine, Clozapine;Amoxapine;Loxapine, Random Forest Classification;PIXEL Calculations;XPac Analysis