Modern Proteomics - Sample Preparation, Analysis and Practical Applications

Modern Proteomics - Sample Preparation, Analysis and Practical Applications

Carrasco, Martin; Mirzaei, Hamid

Springer International Publishing AG

05/2018

533

Mole

Inglês

9783319823577

15 a 20 dias

1385

Descrição não disponível.
Sample Origin.- Sample Preparation for Proteomic Analyses by Mass Spectrometry.- Plant structure and specificity - challenges and sample preparation considerations for proteomics.- Protein Fractionation and Enrichment for Proteomics.- High Performance Liquid Chromatography.- Mass Analyzers.- Top-Down Mass Spectrometry: Proteomics to Proteoforms.- Platforms and pipelines for Proteomics Data Management and Analysis.- Visualization, inspection and interpretation of shotgun proteomics identification results.- Tandem mass spectrum sequencing: an alternative to database search engines in shotgun proteomics.- Protein Inference.- Modification Site Localization in Peptides.- Quantification.- Bioinformatics Tools for the Analysis of Proteomics Data.- Useful Web Resources.- Top-Down Mass Spectrometry: Proteomics to Proteoforms.- Protocol for Standardizing High-to-Moderate Abundance Protein Biomarker Assessments through an MRM-with-Standard-Peptides Quantitative Approach.- Posttranslational Modifications (PTMs) analysis.- Protein-Protein Interaction.- Structural Analysis.- Introduction to Proteomic-Derived Biomarkers.- Discovery of Candidate Biomarkers.- Statistical Approaches to Candidate Biomarker Panel Selection.- Qualification and Verification of biomarker candidates.
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Protein Fractionation;Protein Chromatography;Plant Proteomics;Bioinformatics;Biomarkers;Proteomics