PI3K-mTOR in Cancer and Cancer Therapy

PI3K-mTOR in Cancer and Cancer Therapy

Dey, Nandini; De, Pradip; Leyland-Jones, Brian

Birkhauser Verlag AG

06/2016

294

Dura

Inglês

9783319342092

15 a 20 dias

6033

Descrição não disponível.
PI3K-Akt-mTOR Signaling in Cancer and Cancer Therapeutics.- Part 1: PI3K-mTOR Pathway in Cancers.- The mTOR Complexes in Cancer Cell Metabolism.- PI3K-AKT-mTOR Pathway Co-operates with the DNA Damage Repair Pathway: Carcinogenesis in Triple Negative Breast Cancers and Beyond.- The AKT-mTOR Signaling Pathway for Drug Response Prediction and Prognostic Signatures.- Resistance to PI3K Pathway Inhibition.- Part 2: PI3K-mTOR Pathway in Cancer Medicine.- Combination Therapies Targeting the PI3K/AKT/mTOR Pathways.- Phospho-Inositol-3-Kinase Activity and Dysregulation in Pediatric Leukemia and Lymphoma.- HER2 Signaling Network in Advanced Breast Cancer: Opportunities for Combination Therapies.- The PI3K-mTOR Pathway in Prostate Cancer: Biological Significance and Therapeutic Opportunities.
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apoptosis;cancer;cancer metabolism;drug development;drug resistance;signaling pathway;antibacterial drug resistance