Skin Stress Response Pathways

Skin Stress Response Pathways

Environmental Factors and Molecular Opportunities

Wondrak, Georg T.

Springer International Publishing AG

08/2016

457

Dura

Inglês

9783319431550

15 a 20 dias

9066


ebook

Descrição não disponível.
Preface.



1. The skin lipidome under environmental stress - Technological platforms, molecular pathways and translational opportunities



2. Squalene and skin barrier function: From molecular target to biomarker of environmental exposure



3. Sunlight-induced DNA damage: molecular mechanisms and photoprotection strategies



4. Urocanic Acid and Skin Photodamage: New Light on an Old Chromophore



5. The Skin Extracellular Matrix as a Target of Environmental Exposure: Molecular Mechanisms, Prevention and Repair



6. Nitric Oxide Derivatives and Skin Environmental Exposure to light: From Molecular Pathways to Therapeutic Opportunities



7. Melanocortin 1 receptor (MC1R) as a global regulator of cutaneous UV responses: molecular interactions and opportunities for melanoma prevention

8. The Cutaneous Melanocyte as a Target of Environmental Stressors: Molecular Mechanisms and Opportunities



9. The Role of Epidermal p38 Signaling in Solar UV Radiation-induced Inflammation: Molecular Pathways and Preventive Opportunities



10. UV-Induced Chemokines as Emerging Targets for Skin Cancer Photochemoprevention 11. TLR3 and Inflammatory Skin Diseases: From Environmental Factors to Molecular Opportunities



12. Sirtuins and stress response in skin cancer, aging, and barrier function



13. Cutaneous Opioid Receptors and Stress Responses: Molecular Interactions and Opportunities for Therapeutic Intervention



14. Regulation of Cutaneous Stress Response Pathways by the Circadian Clock: From Molecular Pathways to Therapeutic Opportunities



15. Endocannabinoids and Skin Barrier Function: Molecular Pathways and Therapeutic Opportunities



16. The aryl hydrocarbon receptor (AhR) as an environmental stress sensor and regulator of skin barrier function: Molecular mechanisms and therapeutic opportunities



17. Biological cell protection by natural compounds, a second line of defense against solar radiation



18. The Cutaneous Microbiota as a Determinant of Skin Barrier Function: Molecular Interactions and Therapeutic Opportunities



19. Sensing Environmental Factors: The Emerging Role of Receptors in Epidermal Homeostasis and Whole-Body Health



20. The Cutaneous Circadian Clock as a Determinant of Environmental Vulnerability: Molecular Pathways and Chrono-pharmacological Opportunities



21. Psychological stress as a determinant of skin barrier function: Immunological pathways and therapeutic opportunities



Index
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skin barrier function;skin health;environmental exposure;stress response signaling;small molecule intervention strengthening skin function