Stem Cell Genetics for Biomedical Research

Part I: Stem cells for brain disorders.- Chapter1: Human induced pluripotent stem cell-derived neurons to model and gain insights into Alzheimer's disease pathogenesis.- Chapter2: Modeling schizophrenia with human stem cells.- Chapter3: Rett Syndrome and Stem Cell research.- Chapter4: Stem Cell Applications in Spinal Cord Injury: A Primer.- Chapter5: Cell-Based Therapy for Retinal Degenerative Disease.- Chapter6: Past, present and future of cell based-therapy in progressive multiple sclerosis.- Part II: Stem cells for cardiovascular diseases.- Chapter7: Cardiac Stem Cells: a plethora of potential therapies for myocardial regeneration within reach.- Chapter8: Human Induced Pluripotent Stem Cell-derived Cardiomyocytes in the Evaluation of Cardiotoxic Potential of Drugs.- Part III: Stem cells for general medicine.- Chapter9: Regenerative medicine for diabetes treatment: new ?-cell sources.- Chapter10: Dental pulp stem cells promote wound healing and muscle regeneration.- Chapter11: From bench to bedside of mesenchymal Stem Cells use for Rheumatoid Arthritis treatment.- Chapter12: Stem Cells and Cancer.- Chapter13: The relevance of induced pluripotent stem cells for the study of physiological and premature aging.- Part IV: Technical challenges and future.- Chapter14: Pluripotent stem cell banks.- Chapter15: Genetic and Epigenetic engineering: the CRISPR/Cas9 era.

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• Biologia do desenvolvimento
• Genética médica
• Pesquisa médica

disease modeling;cell transplantation;somatic;brain disorders;cardiovascular;therapeutics