Future of HIV-1 Therapeutics

Future of HIV-1 Therapeutics

Resistance Is Futile?

Goodsell, David S.; Richman, Douglas D.; Torbett, Bruce E.

Springer International Publishing AG

10/2016

254

Mole

Inglês

9783319374505

15 a 20 dias

4044

Descrição não disponível.
HIV Therapy - Looking Towards the Future.- Computational challenges of structure-based approaches applied to HIV.- Nucleocapsid Protein: A Desirable Target For Future Therapies Against HIV-1.- HIV-1 integrase multimerization as a therapeutic target.- Targeting HIV transcription: The quest for a functional cure.- Targeting the HIV RNA Genome: High-Hanging Fruit Only Needs a Longer Ladder.- HIV-1 Gag: An Emerging Target for Antiretroviral Therapy.- The Triple Threat of HIV-1 Protease Inhibitors.- Illustrations of the HIV Life Cycle.
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Fragment-based drug design;HIV Gag protein;HIV capsid;HIV integrase protein;HIV matrix;HIV nucleocapsid protein;HIV protease;HIV reverse transcriptase protein;HIV stem-loop;HIV transcription;HIV-1 antiretroviral treatment;HIV-1 drug resistance;HIV-1 illustrations;HIV-1 latency;High-throughput virtual screening;Human immunodeficiency virus;LEDGF/p75 protein;Rev protein;Structure-based drug design;Tat/TAR/P-TEFb complex;antibacterial drug resistance