Biomolecular Interfaces
-15%
portes grátis
Biomolecular Interfaces
Interactions, Functions and Drug Design
Fernandez Stigliano, Ariel
Springer International Publishing AG
05/2015
372
Dura
Inglês
9783319168494
15 a 20 dias
7155
Descrição não disponível.
The Aqueous Interface of a Soluble Protein or the Birth of Epistructural Biology.- Electrostatic Exploration of Biomolecular Interfaces: The Chemical Function of Interfacial Water.- Semiempirical Solution to the Protein Folding Problem Through a Combination of Structural and Epistructural Approaches.- Packing Defects and Protein Hydration: Dynamics of the Aqueous Interface.- Proteins in the Order-Disorder Twilight: Unstable Interfaces Promote Protein Aggregation.- Evolution of Protein Structure Degradation and Lessons for the Drug Designer.- Chemical Functionality of the Aqueous Interface in Soluble Proteins.- The Biomolecular Interface as a Selectivity Filter for Drug-Based Targeted Therapy.- Wrapping-Based Re-Engineering of an Anticancer Drug to Make it Safer.- Biomolecular Interfaces Provide Universal Markers for Drug Specificity and Personalized Medicine.- Controlling Induced Folding Through Wrapping Drug Design.- Wrapping Drug Combinations for Therapeutic Editing of Side Effects: Systems Biology Meets Wrapping Technology.- Multi-Target Control of Drug Impact: A Therapeutic Imperative in Cancer Systems Biology.- Engineering Therapeutic Alignments between Immune Response and Molecularly Targeted Cancer Treatment.- High-Level Quantum Chemistry Empowers the Wrapping Technology for Drug Design.- Epilogue.- Appendix 1. Code for Dehydron Identification.- Appendix 2. Solutions of Problems.
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Biological water;Biomolecular interface;Chemical physics;Drug design;Hydrogen bond;Molecular biophysics;Protein interactions;Protein-Ligand Interactions
The Aqueous Interface of a Soluble Protein or the Birth of Epistructural Biology.- Electrostatic Exploration of Biomolecular Interfaces: The Chemical Function of Interfacial Water.- Semiempirical Solution to the Protein Folding Problem Through a Combination of Structural and Epistructural Approaches.- Packing Defects and Protein Hydration: Dynamics of the Aqueous Interface.- Proteins in the Order-Disorder Twilight: Unstable Interfaces Promote Protein Aggregation.- Evolution of Protein Structure Degradation and Lessons for the Drug Designer.- Chemical Functionality of the Aqueous Interface in Soluble Proteins.- The Biomolecular Interface as a Selectivity Filter for Drug-Based Targeted Therapy.- Wrapping-Based Re-Engineering of an Anticancer Drug to Make it Safer.- Biomolecular Interfaces Provide Universal Markers for Drug Specificity and Personalized Medicine.- Controlling Induced Folding Through Wrapping Drug Design.- Wrapping Drug Combinations for Therapeutic Editing of Side Effects: Systems Biology Meets Wrapping Technology.- Multi-Target Control of Drug Impact: A Therapeutic Imperative in Cancer Systems Biology.- Engineering Therapeutic Alignments between Immune Response and Molecularly Targeted Cancer Treatment.- High-Level Quantum Chemistry Empowers the Wrapping Technology for Drug Design.- Epilogue.- Appendix 1. Code for Dehydron Identification.- Appendix 2. Solutions of Problems.
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
