Interleukin 12: Antitumor Activity and Immunotherapeutic Potential in Oncology

Interleukin 12: Antitumor Activity and Immunotherapeutic Potential in Oncology

Zagozdzon, Radoslaw; Jakobisiak, Marek; Lasek, Witold

Springer International Publishing AG

10/2016

75

Mole

Inglês

9783319469058

15 a 20 dias

1416


ebook

Descrição não disponível.
*Biology of IL-12 -1.1.Molecular structure of IL-12,-1.2.IL-12 receptor, -1.3.Regulation of IL-12 expression,- 1.4.Role of IL-12 in antitumor immunity,- 1.5.References 2*Antitumor effects of IL-12 in preclinical studies -2.1.IL-12 in a single-agent therapy and in the combined treatment of animal tumors,-2.2.Experimental IL-12-based gene therapy,-2.3.References 3*Clinical trials with IL-12 in cancer immunotherapy -3.1.Early clinical studies,-3.2.Cutaneous T cell lymphoma (CTCL),-3.3.Hodgkin's and non-Hodgkin's lymphoma,-3.4.Kaposi's sarcoma,-3.5.Trends in IL-12-based approaches in oncology,-3.6.References.
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Interleukin 12;Antitumor Effects;Cancer;Immunotherapy;Clinical Trials