Mitochondrial Dysfunction in Neurodegenerative Disorders

Mitochondrial Dysfunction in Neurodegenerative Disorders

Turnbull, Doug M.; Simcox, Eve M.; Duchen, Michael R.; Reeve, Amy K.

Springer International Publishing AG

05/2018

380

Mole

Inglês

9783319803944

15 a 20 dias

6626

Descrição não disponível.
Part I.
Mitochondria and Neurodegenerative Disease.- An Introduction
to Mitochondria, Their Structure and Functions.- Part II.
Mitochondrial Dysfunction: Causes and Effects?.- Neurodegeneration in Mitochondrial Disorders.- The Ageing Brain,
Mitochondria and Neurodegeneration.- Mitochondrial Genes and Neurodegenerative Disease.- Mitochondrial
Signalling and Neurodegeneration.- Part III. Functional Consequences of
Mitochondrial Dysfunction.- Life on the Edge: Determinants of Selective
Neuronal Vulnerability in Parkinson's Disease.- Mitochondrial
Dynamics and Neurodegeneration.- Mitochondrial Dysfunction and Transport in Demyelinating Disease with Inflammation.-
Mitochondria,
the Synapse, and Neurodegeneration.- Protein Misfolding and
Aggregation: Implications for Mitochondrial Dysfunction and Neurodegeneration.-
Mitochondrial Degradation, Autophagy and
Neurodegenerative Disease.- The Deleterious
Duo of Neurodegeneration: Lysosomes and Mitochondria.- PartIV. Measuring the
Contribution of Mitochondrial Dysfunction to Neurodegenerative Disease.- Can
We Accurately Model Mitochondrial Dysfunction in Neurodegeneration?.- Mitochondrial
Function and Dynamics Imaged In Vivo.-
Part V. The Future.- Development
of Treatments and Therapies to Target Mitochondrial Dysfunction.- Summary and Conclusions.
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Alzheimer's disease;Parkinson's disease;mitochondrial dysfunction;multiple sclerosis;neurodegenration;neurodegenrative disorder