Revisiting Barrett's Esophagus

Part I Morphologic backgrounds 1 Macroscopic anatomy of esophagus Stefania Montagnani, Clotilde Castaldo 2 Microscopic anatomy and histology of esophagus Stefania Montagnani, Franca Di Meglio Part II Epidemiology and natural history 3 Definition and epidemiology of Barrett's esophagus Alessandra Romiti, Rocco Maurizio Zagari 4 Pathophysiolgy of esophageal reflux disease and natural history of Barrett's esophagus Paola Iovino, Antonella Santonicola, Nigel J Trudgill Gastro-esophageal reflux disease Natural history of Barrett's esophagus Natural history of non dysplastic Barrett's esophagus Natural history of Barrett's esophagus indefinite for dysplasia Natural history of Barrett's esophagus with low grade dysplasia Natural history of Barrett's esophagus with high grade dysplasia 5 Obesity: Barrett's esophagus and esophageal cancer risk Jan Marc Chevallier, Sonja Chiappetta, Mario Musella Introduction Factors leading to GERD Obesity, Barrett's ulcer, and risk of cancer Bariatric surgery and risk of GERD GERD following restrictive procedures GERD following gastric by-pass procedures Part III Diagnosis 6 First level endoscopy in Barrett's esophagus: endoscopic pictures, Prague classification and biopsy protocols Massimo Conio, Antonella De Ceglie, Mattia Crespi Endoscopic pictures Prague classification Biopsy protocol 7 Augmented endoscopy in Barrett's esophagus: zoom endoscopy, traditional, and virtual chromoendoscopy Giuseppe Galloro, Raffaele Manta, Nico Pagano, Teresa Russo, Donato Alessandro Telesca, Andrea Parodi, Cesare Formisano Introduction Traditional chromoendoscopy High definition, zoom, and magnifying endoscopy Computed virtual chromoendoscopy 8 Confocal LASER endomicroscopy in Barrett's esophagus: is it a clinical resource or still a research procedure? Giovanni Domenico De Palma, Gianluca Cassese, Gaetano Luglio Confocal LASER endomicroscopy: theoretical and practical bases Technical notes CLE for Barrett's esophagus management Current limitations and possibilities for future development Conclusions 9 Histology: the different points of view on Barrett's esophagus Vincenzo Villanacci, Karel Geboes, Tiziana Salviato, Gabrio Bassotti Normal esophagus Endoscopic and microscopic diagnosis of Barrett's esophagus Is all intestinal metaplasia equivalent to Barrett's esophagus? Dysplasia in Barrett's esophagus 10 The role of molecular biology in diagnosis and follow-up of Barrett's esophagus Karen Geboes, Anne Hoorens Introduction Molecular pathways implicated in development of Barrett's esophagus Molecular markers for the diagnosis Markers for the diagnosis of dysplasia Genome-wide association studies for the development of Barrett's esophagus Molecular pathways implicated in the transition of Barrett's esophagus to early adenocarcinoma Molecular biology of progression to adenocarcinoma Molecular markers for the diagnosis of progression to EAC. Genetic changes involved in the progression from BE to EAC. Biomarker development Conclusions 11 Timing and protocols of clinical and endoscopic surveillance of Barrett's esophagus Carlo Calabrese, Marco Salice, Nico Pagano, Raffaele Manta, Fernando Rizzello Protocol Part IV Treatments 12 Lifestyles, medical therapy, and chemoprevention Giancarlo Sarnelli, Alessandra D'Alessandro, Raf Bisschops Physical activity and diet Smoking and alcohol intake Chemoprevention 13 Photodynamic therapy Raffaele Manta, Dolores Sgambato, Nico Pagano, Giuseppe Galloro Introduction Technique Data of literature Limits Controindications State of the art 14 Cryotherapy Nico Pagano, Raffaele Manta, Giuseppe Galloro Introduction Physical principles and technical consideration Clinical results Conclusions 15 Endoscopic resections: EMR and ESD Filippo Catalano, Seichiro Abe, Yutaka Saito 16 Radiofrequency ablation Jason Samarasena, David Lee, Kenneth J Chang Introduction Indications Equipment Technique Post procedure Efficacy Adverse events Cost-effectiveness analysis Buried Barrett's Esophagus Conclusions 17 What we have to do after the treatment of metaplasia or dysplasia in Barrett's esophagus? Protocols and timing of follow-up in the treated patient Jose Miguel Esteban Introduction Endoscopic therapies of Barrett's esophagus Surveillance after endoscopic therapy Surveillance Strategies Publications regarding Protocols and Timing for surveillance Protocols and timing of follow-up in the treated patient recommendations Special considerations Conclusions 18 Is there a role for the surgeon in therapeutic management of Barrett esophagus? Uberto Fumagalli Romario, Paul Magnus Schneider Introduction Does BE regress after ARS and/or does ARS reduce the cancer risk in BE? Which type of surgery for short and long segment Barrett's esophagus ? Role of ARS to prevent BE remission following endoscopic ablation procedures Role of ARS to prevent BE recurrence or progression after endoscopic ablation procedures 19 Early adenocarcinoma in Barrett esophagus: is this an endoscopic or a surgical problem? Antonello Trecca, Takuji Gotoda

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• Cirurgia geral
• Cirurgia oncológica
• Gastroenterologia